In a new study, people with moderate-to-severe gum disease were found to have altered connections between different brain regions, potentially increasing their risk of dementia.
Gum disease may impair brain function, potentially increasing the risk of Alzheimer’s disease, a new study finds.
Researchers compared MRI brain scans of 51 adults with normal cognition. 11 had healthy gums and 40 had gum disease. Participants with gum disease, especially moderate-to-severe cases, had altered connections between and within different brain regions.
The researchers say these findings suggest periodontitis may be a potential risk factor for brain damage and an early warning sign for cognitive decline.
Bacteria from gum infections can invade brain tissue promoting an immune response.
The authors say the findings also suggest treating gum disease could play a role in preventing Alzheimer’s.
They say, “The present study has important implications for improving not only oral health but also neurological health worldwide.”
Source: Journal of Periodontology
Author Affiliations: Anhui Medical University
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